Optimal matching of animals guarantees balanced intervention groups
Matched modelling of intervention effects improves statistical power
Model-based power analysis enables tailoring sufficient sample sizes
To use and tailor the features of the hamlet R-package in your own analysis scripts it can be easily installed locally. The latest version of the package is available at CRAN
Install by invoking, e.g.,
in an R terminal.
Laajala TD, Jumppanen M, Huhtaniemi R, Fey V, Kaur A, Knuuttila M, Aho E, Oksala R, Westermarck J, Mäkelä S, Poutanen M, Aittokallio T. (2016). Optimized design and analysis of preclinical intervention studies in vivo. Scientific Reports 6, 30723. doi:10.1038/srep30723 [Free full text at PubMed Central (PMC4969752)]